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February 8, 2008
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| Photo by Richard Anderson |
A story published this week in ScienceDaily reported on the breakthrough work of a University of Minnesota research team in discovering a new way to turn off T-cell genes in the human immune system. CSE professor George Karypis, part of the research team, used computer programs to analyze the genes as part of the project.
Through a process called mRNA decay, turning off genes helps to regulate the body’s immune system after battling an infection. In this project, researchers used computational analysis and molecular biology to find a new way to turn off the T-cells. This breakthrough could help develop new drugs to help people fighting various diseases, such as lupus, and possibly help fight cancer.
"This discovery would not have been possible without the interdisciplinary collaboration between molecular biologists and computer scientists," said Paul Bohjanen, M.D., Ph.D., co-director of the Center for Infectious Diseases and Microbiology Translational Research (CIDMTR) and principal investigator of the study.
For more information, visit ‘Pathway to Turn off Immune System Cells Discovered.’
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